Premier League Matchday 27 Picks: Derby Day in Manchester

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Updated: March 4, 2021

If you feel like the theme of the English Premier League sounds the same this week as it has in previous weeks, it’s because very little has changed at the top.

Another Manchester City victory has the Premier League powerhouse one step closer to an emphatic title, while second-place Manchester United and third-place Leicester City remain in their own tier but are both struggling to secure points. Meanwhile, the race for the remaining European places is getting a little more interesting, with the current spot holders struggling and the teams directly behind them gaining ground.

Here are our top Premier League betting plays for Matchday 27.

Premier League predictions for Matchday 27

Burnley vs Arsenal

Do the Gunners have enough in them to roar out of the middle of the Premier League table and steal a European place? The odds are not in their favor as they prepare to face host Burnley on Saturday. Arsenal sit 10th in the table through 26 uninspiring weeks, with an identical number of wins and losses and an equally mediocre plus-seven goal differential for the season.

The Gunners have gone more than a month without posting a clean sheet, but are in prime position to end that drought this weekend against a Burnley side that has recorded a league-low 19 goals. Burnley stole a 1-0 away win in their previous meeting back in December, but Arsenal played the last 40 minutes of that game with 10 men. We like them to return the favor Saturday.

PICK: Arsenal clean sheet (+120)

Manchester City vs Manchester United

It’s derby time in Manchester, with City and United tangling as the top two teams in the table. But Man City are in an entirely different stratosphere at the moment, having reeled off an incredible 21 consecutive victories across all competitions – a run that includes a thorough 2-0 triumph over rival Man United in a Carabao Cup encounter back on Jan. 6.

You can be sure that United will struggle mightily to do much offensively against a City side that has allowed just eight goals over the course of its winning streak. It’s also worth noting that Man City have scored in just one of the previous five meetings between the teams. This has all the makings of a low-scoring affair, leading to a betting choice that comes with rather solid odds.

PICK: Under 2.5 (+110)

West Ham vs Leeds United

The final game of Matchday 27 could feature plenty of fireworks, with a pair of top-eight offenses in West Ham and Leeds United clashing at London Stadium. West Ham maintain a tenuous grip on fourth place (and the final Champions League qualifying spot) entering Thursday and are modest favorites against a Leeds side that has stumbled to losses in three of its last four.

There isn’t much in the way of recent head-to-head history, but these teams combined for three goals in their previous encounter back on Dec. 11. Both teams average above 2.5 goals per game on the season, with Leeds actually above 3.0 so far. This might not be your biggest payday of the weekend, but it certainly represents one of the safer plays you’ll make.

PICK: Over 2.5 (-150)

Premier League betting card for Matchday 27

  • Arsenal clean sheet (+120)
  • Manchester City-Manchester United Under 2.5 (+110)
  • West Ham-Leeds Over 2.5 (-150)
Premier League parlays

Did you know that if you parlayed our Premier League Matchday 27 picks, you could win $67.00 on a $10 bet?

Use our Premier League parlay calculator to create your own parlays and see their potential payouts. 

Where can I bet on Premier League soccer?

You can bet on Premier League soccer at most online sportsbooks and mobile apps. Find the best sportsbooks in your region to bet on Premier League soccer odds.


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