Angels vs A’s MLB Odds, Picks and Predictions May 28

Updated: May 28, 2021

Shohei Ohtani will start tonight – assuming he makes it to the arena on time – and will get to counter Sean Manaea, who has been highly inconsistent this season.

Photo By – USA TODAY Sports

The Oakland Athletics host the Los Angeles Angels at RingCentral Coliseum in Oakland, California in the second of a four-game series on Friday, May 28. The first pitch should be tossed at around 9:40 p.m. ET, and this figures to be a pretty exciting game. 

Will Shohei Ohtani find a way to lead Los Angeles to a win in this one? Keep reading our Angels vs. Athletics

Angels vs A’s game info

Location: RingCentral Colesium, Oakland, CA
Date: Friday, May 28, 2021
Time: 9:40 p.m. ET

Angels vs A’s odds

Odds via the Covers Line, an average comprised of odds from multiple sportsbooks.

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Angels vs A’s betting preview

Starting pitchers

Shohei Ohtani (1-0, 2.37 ERA): Ohtani was supposed to start on Thursday, but he ended up being a late scratch. Still, Ohtani is finally looking healthy out there and he has quickly shown the world what he is capable of as both a hitter and a pitcher. He’s yet to work into the eighth inning of a game, so he hasn’t shown that he can go very deep into his outings, but he doesn’t need to if he’s blanking opponents and putting the bullpen in a great position.

Sean Manaea (3-2, 4.17 ERA): Manaea’s inconsistency can be infuriating. The lefty was rock solid against this very Angels team on Sunday, but he had given up 10 earned runs on 20 hits in his previous two starts. Oakland will be hoping for more of what he brought in his last outing against this lineup, but you just never know what you’re going to get with him. 


Be sure to monitor the gametime conditions with our MLB weather info.

Key injuries

Angels: OF Mike Trout (out), OF Dexter Fowler (out), SS Jose Iglesias (questionable).
A’s: 1B Mitch Moreland (out), RP Trevor Rosenthal (out).
Find our latest MLB injury reports.

Betting trend to know

The Angels are 4-0 in their last four games against left-handed starters. Find more MLB betting trends for Angels vs. A’s.

Moneyline pick

Manaea pitched well against the Angels on Sunday, but they should be a bit more prepared this time around. This team also happens to have quite a few guys that are more comfortable batting against left-handed starters, and that makes this lineup a bit more dangerous. 

Without Mike Trout, it will take a group effort for Los Angeles to win games. With that said, keep an eye on guys like Anthony Rendon and David Fletcher. Rendon has struggled to stay health with the Angels, but it’s only a matter of time before he gets going this season. He has homered off Manaea once in his career and it wouldn’t be shocking if he does it again. Meanwhile, David Fletcher is 2 for 7 with a double and two RBI against the lefty. Los Angeles also has Ohtani to try and help his own cause, and Jared Walsh has a ton of pop. Both prefer to hit against righties, but they can easily make Manaea pay for a mistake. 

Ohtani being on the mound also means that the Angels will have their best starter out there. It’s never a guarantee that a lousy team will beat a good one, but Los Angeles has a great chance tonight. 

PREDICTION: Angels ML +120

Covers MLB betting analysis

Over/Under pick

Ohtani has allowed just three earned runs in his last 16.2 innings on the mound, and he is starting to finally put it all together as a starter. His bat-missing ability should really throw Oakland off in this game. Meanwhile, Manaea might not repeat Sunday’s performance against the Angels in this one, but he doesn’t have to in order to help this total. If he’s a bit worse and Ohtani has it going, this thing should end up settling at around six or seven. Will it be a sweat? Probably. But we’re confident in the Under being the right call. 

PREDICTION: Under 7.5 (-108)

Angels vs A’s betting card

  • Angels ML +120
  • Under 7.5 (-108)

Picks made on 5/28/2021 at 11:30 a.m. ET

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