Champions League Tips and Predictions for Round of 16

Updated: February 22, 2021

Manchester City have rolled to 18 consecutive victories across all competitions and have given up a goal in just seven of their past 25 matches overall.

Photo By – USA TODAY Sports

After an entertaining opening slate of UEFA Champions League elimination series games, things are about to pick up this week.

The Top 2 favorites to win the Champions League title are both in action, with Manchester City (+300) playing its road leg against German side Borussia Monchengladbach, and Bundesliga favorites Bayern Munich (+375) tangling with host Lazio. Real Madrid are also in action in what should be the most entertaining game of this week’s slate.

Here are our top UEFA Champions League betting picks for February 23-24:

Champions League predictions for February 23-24

Atletico Madrid vs Chelsea

Atletico might enter this week’s Champions League action as the leaders of La Liga, but they haven’t shown terrific form of late as they prepare to host Chelsea. The Spanish stalwarts have just one victory from their previous four matches and are coming off a particularly egregious 2-0 home loss to Levante. Chelsea, meanwhile, have played eight straight games without a defeat.

Atletico will be down several key players, most notably Kieran Trippier, and have shown cracks in their form – particularly at home, where they’ve allowed five goals in three games after surrendering just six in their previous 11. Chelsea have shown solid form of late, and are well-positioned to snag the single point on the road and take control of this two-leg elimination series.

TIP: Draw (+200)

Lazio vs Bayern Munich

Lazio bring a seven-game home winning streak into one of their toughest tests of the season – a Tuesday evening date with powerhouse Bayern Munich. The visitors are coming off a 2-1 away loss to Eintracht Frankfurt and have earned just one point over their past two games, but they’re massive favorites against a Lazio side fortunate to sit fifth in the Italian League table.

Lazio have a modest plus-8 goal differential for the season, and normally that wouldn’t cut it against a Bayern side that boasts an outstanding plus-31 scoring margin. But with Bayern forced to play without a handful of star players – including Thomas Muller – the door is wide open for Lazio to extend their home dominance by snagging a draw or outright victory here.

TIP: Lazio Win or Draw (+100)

Atalanta vs Real Madrid

Two of the most prolific teams in their respective domestic leagues get ready to air it out Wednesday evening as Real Madrid visit Atalanta. Real come in as slight +190 underdogs despite boasting the third-highest goal total in La Liga to date with 42 goals over 24 matches. Atalanta (+125) have been even better in Serie A, racking up 53 goals through 23 league matches.

Both sides produced more modest goal totals in the Champions League group stage, with Real Madrid scoring 11 times in six games – one more than Atalanta. And each team has converted the Under in their previous three Champions League matches. This one’s going to leave you sweating all match, but we recommend the U2.5 based on both teams’ recent tourney trends.

TIP: Under 2.5 (+130)

Borussia Monchengladbach v. Manchester City

The most one-sided set of odds belongs to the final game of this week’s Champions League schedule, as Manchester City enter as -334 favorites against Borussia Monchengladbach (+800). Man City cruised to a 5-0-1 record and a plus-12 goal margin in the group stage, while Monchengladbach finished second in Group B on the strength of 16 group stage goals.

With respect to their German League counterparts, Man City are on an entirely different level at the moment. They’ve rolled to 18 consecutive victories across all competitions and have given up a goal in just seven of their past 25 matches overall. We like the visitors to not only pull out the victory, but to do so via another clean sheet.

TIP: Manchester City Win/Clean Sheet (+125)

Champions League betting card for February 23-24

  • Atletico Madrid-Chelsea draw (+200)
  • Lazio win or draw (+100)
  • Atalanta-Real Madrid Under 2.5 (+130)
  • Manchester City win/clean sheet (+125)

Champions League parlays

Did you know that if you parlayed our Champions League Round of 16 picks, you could win $300.50 on a $10 bet?

Use our Champions League parlay calculator to create your own parlays and see their potential payouts. 

Where can I bet on Champions League soccer?

You can bet on Champions League soccer at most online sportsbooks and mobile apps. Find the best sportsbook in your region in our top listing section.

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