Matchups, Times and Opening Lines

Updated: May 17, 2021

The Rams and Aaron Donald will get Week 5 underway with a Thursday Night Football matchup vs. the Seahawks. The game opened as a pick’em at The SuperBook.

Photo By – USA TODAY Sports

The NFL schedule is finally released! We now know what each team’s matchups will be in this new 18-week season, including the game list for Week 5.

The NFL Week 5 matchups begin with a Thursday Night clash between the Rams and Seahawks, features an international game between the Jets and Falcons and is capped off by a Monday Night Football matchup between the Colts and Ravens. 

Here is the list of all the NFL Week 5 matchups, times and opening spreads.

These are the opening NFL odds for Week 5, headlined by the Rams in a pick’em visiting the Seahawks and Kansas City favored by 4.5-points against Buffalo.

Matchup Time Spread Over/Under
Rams at Seahawks  Thurs, 8:20 p.m. ET PK 48
Jets at Falcons* Sun, 9:30 a.m. ET Falcons -3 48
Lions at Vikings Sun, 1 p.m. ET Vikings -8.5 48
Saints at Washington Sun, 1 p.m. ET Washington +1.5 46.5
Patriots at Texans Sun, 1 p.m. ET Texans +6 46.5
Dolphins at Buccaneers Sun, 1 p.m. ET Buccaneers -7.5 50.5
Packers at Bengals Sun, 1 p.m. ET Bengals +3 47.5
Broncos at Steelers Sun, 1 p.m. ET Steelers -4.5 45
Eagles at Panthers Sun, 1 p.m. ET Panthers -3 47.5
Titans at Jaguars Sun, 1 p.m. ET Jaguars +2.5 48
Browns at Chargers Sun, 4:05 p.m. ET Chargers +1.5 47.5
Bears at Raiders Sun, 4:05 p.m. ET Raiders -3.5 46.5
49ers at Cardinals Sun, 4:25 p.m. ET PK 46.5
Giants at Cowboys Sun, 4:25 p.m. ET Cowboys -5.5 48.5
Bills at Chiefs Sun, 8:20 p.m. ET Chiefs -4.5 54.5
Colts at Ravens Mon, 8:15 p.m. ET Ravens -4 49

*This game will be played in London, England.
Odds courtesy of The SuperBook as of May 16, 2021

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